IEEE ISSPIT 2016 is the sixteenth in a series of international symposia that aims to cover a wide range of topics in the intersection of signal processing and information technology and to become a fertile ground for discussions between the two research and development communities. Apart from sessions that will present new research results, tutorials and special sessions will be offered as well. Papers describing original work are invited in the general fields covered by ISSPIT, with an emphasis on the topics listed below. Accepted papers will be published in the Proceedings of IEEE ISSPIT 2016 and will be available via IEEE Xplore. Acceptance will be based on quality, relevance, and originality. A contest for Best Paper Awards (senior and student) will be held.